Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A

Cardiac hypertrophy is a common and often lethal complication of arterial hypertension. Atrial natriuretic peptide (ANP) has been postulated to exert local antihypertrophic effects in the heart. Thus, a loss of function of the ANP receptor guanylyl cyclase-A (GC-A) might contribute to the increased...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Holtwick, Rita, van Eickels, Martin, Skryabin, Boris V., Baba, Hideo A., Bubikat, Alexander, Begrow, Frank, Schneider, Michael D., Garbers, David L., Kuhn, Michaela
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 2003
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154444/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12727932/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17061
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