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Mechanism of methanol oxidation by quinoprotein methanol dehydrogenase

At neutral pH, oxidation of CH(3)OH → CH(2)O by an o-quinone requires general-base catalysis and the reaction is endothermic. The active-site –CO(2)(−) groups of Glu-171 and Asp-297 (Glu-171–CO(2)(−) and Asp-297–CO(2)(−)) have been considered as the required general base catalysts in the bacterial o...

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Detalhes bibliográficos
Main Authors: Zhang, Xiaodong, Reddy, Swarnalatha Y., Bruice, Thomas C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020142/
https://ncbi.nlm.nih.gov/pubmed/17215371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610126104
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