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Determination of enzyme mechanisms by molecular dynamics: Studies on quinoproteins, methanol dehydrogenase, and soluble glucose dehydrogenase

Molecular dynamics (MD) simulations have been carried out to study the enzymatic mechanisms of quinoproteins, methanol dehydrogenase (MDH), and soluble glucose dehydrogenase (sGDH). The mechanisms of reduction of the orthoquinone cofactor (PQQ) of MDH and sGDH involve concerted base-catalyzed proton...

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Detaylı Bibliyografya
Asıl Yazarlar: Reddy, Swarnalatha Y., Bruice, Thomas C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2279812/
https://ncbi.nlm.nih.gov/pubmed/15273299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04673404
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