Učitavanje...
RITA, a novel modulator of Notch signalling, acts via nuclear export of RBP-J
The evolutionarily conserved Notch signal transduction pathway regulates fundamental cellular processes during embryonic development and in the adult. Ligand binding induces presenilin-dependent cleavage of the receptor and a subsequent nuclear translocation of the Notch intracellular domain (NICD)....
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| Glavni autori: | , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020113/ https://ncbi.nlm.nih.gov/pubmed/21102556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.289 |
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