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Nek2B, a novel maternal form of Nek2 kinase, is essential for the assembly or maintenance of centrosomes in early Xenopus embryos

Nek2, a NIMA-related kinase, has been postulated to play a role in both the meiotic and mitotic cell cycles in vertebrates. Xenopus has two Nek2 splice variants, Nek2A and Nek2B, which are zygotic and maternal forms, respectively. Here we have examined the role of Nek2B in oocyte meiosis and early e...

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Detalhes bibliográficos
Main Authors: Uto, Katsuhiro, Sagata, Noriyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC302008/
https://ncbi.nlm.nih.gov/pubmed/10775266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.8.1816
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