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Nek2B, a novel maternal form of Nek2 kinase, is essential for the assembly or maintenance of centrosomes in early Xenopus embryos

Nek2, a NIMA-related kinase, has been postulated to play a role in both the meiotic and mitotic cell cycles in vertebrates. Xenopus has two Nek2 splice variants, Nek2A and Nek2B, which are zygotic and maternal forms, respectively. Here we have examined the role of Nek2B in oocyte meiosis and early e...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Uto, Katsuhiro, Sagata, Noriyuki
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302008/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10775266/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.8.1816
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