Alternative Splicing of the Human Cytomegalovirus Major Immediate-Early Genes Affects Infectious-Virus Replication and Control of Cellular Cyclin-Dependent Kinase

The major immediate-early (MIE) gene locus of human cytomegalovirus (HCMV) is the master switch that determines the outcomes of both lytic and latent infections. Here, we provide evidence that alteration in the splicing of HCMV (Towne strain) MIE genes affects infectious-virus replication, movement...

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Bibliographische Detailangaben
Hauptverfasser: Du, Guixin, Dutta, Nirmal, Lashmit, Philip, Stinski, Mark F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020018/
https://ncbi.nlm.nih.gov/pubmed/21068259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01173-10
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