Inhibition of Cellular DNA Synthesis by the Human Cytomegalovirus IE86 Protein Is Necessary for Efficient Virus Replication

Human cytomegalovirus (HCMV) expresses several proteins that manipulate normal cellular functions, including cellular transcription, apoptosis, immune response, and cell cycle control. The IE2 gene, which is expressed from the HCMV major immediate-early (MIE) promoter, encodes the IE86 protein. IE86...

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Bibliographic Details
Main Authors: Petrik, Dustin T., Schmitt, Kimberly P., Stinski, Mark F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1440472/
https://ncbi.nlm.nih.gov/pubmed/16571804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.8.3872-3883.2006
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