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The Autoregulatory and Transactivating Functions of the Human Cytomegalovirus IE86 Protein Use Independent Mechanisms for Promoter Binding

The functions of the human cytomegalovirus (HCMV) IE86 protein are paradoxical, as it can both activate and repress viral gene expression through interaction with the promoter region. Although the mechanism for these functions is not clearly defined, it appears that a combination of direct DNA bindi...

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Autori principali: Petrik, Dustin T., Schmitt, Kimberly P., Stinski, Mark F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900308/
https://ncbi.nlm.nih.gov/pubmed/17376893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02437-06
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