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Phosphorylation of RIG-I by Casein Kinase II Inhibits Its Antiviral Response
RIG-I is an intracellular RNA virus sensor that mediates a signaling pathway that triggers the alpha/beta interferon (IFN-α/β) immune defenses. However, the mechanism for regulation of RIG-I activity remains largely unknown. Here we show that RIG-I activity is regulated by phosphorylation and dephos...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020001/ https://ncbi.nlm.nih.gov/pubmed/21068236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01734-10 |
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