Indoleamine 2,3-Dioxygenase Mediates the Antiviral Effect of Gamma Interferon against Hepatitis B Virus in Human Hepatocyte-Derived Cells

Alpha interferon (IFN-α) is an approved medication for chronic hepatitis B. Gamma interferon (IFN-γ) is a key mediator of host innate and adaptive antiviral immunity against hepatitis B virus (HBV) infection in vivo. In an effort to elucidate the antiviral mechanism of these cytokines, 37 IFN-stimul...

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Hlavní autoři: Mao, Richeng, Zhang, Jiming, Jiang, Dong, Cai, Dawei, Levy, Jessica M., Cuconati, Andrea, Block, Timothy M., Guo, Ju-Tao, Guo, Haitao
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019998/
https://ncbi.nlm.nih.gov/pubmed/21084489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01998-10
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