MyD88-Dependent Signaling Protects against Anthrax Lethal Toxin-Induced Impairment of Intestinal Barrier Function

MyD88-deficient mice were previously shown to have increased susceptibility to Bacillus anthracis infection relative to wild-type animals. To determine the mechanism by which MyD88 protects against B. anthracis infection, knockout mice were challenged with nonencapsulated, toxigenic B. anthracis or...

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Hlavní autoři: Okugawa, Shu, Moayeri, Mahtab, Eckhaus, Michael A., Crown, Devorah, Miller-Randolph, Sharmina, Liu, Shihui, Akira, Shizuo, Leppla, Stephen H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Host Response and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019866/
https://ncbi.nlm.nih.gov/pubmed/20974827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00963-10
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