SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation

The eukaryotic cell cycle is regulated by multiple ubiquitin-mediated events, such as the timely destruction of cyclins and replication licensing factors. The histone H4 methyltransferase SET8 (Pr-Set7) is required for chromosome compaction in mitosis and for maintenance of genome integrity. In this...

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Bibliographic Details
Main Authors: Jørgensen, Stine, Eskildsen, Morten, Fugger, Kasper, Hansen, Lisbeth, Yoo Larsen, Marie Sofie, Kousholt, Arne Nedergaard, Syljuåsen, Randi G., Trelle, Morten Beck, Nørregaard Jensen, Ole, Helin, Kristian, Sørensen, Claus Storgaard
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2011
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019552/
https://ncbi.nlm.nih.gov/pubmed/21220508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009076
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