The histone methyltransferase SET8 is required for S-phase progression

Chromatin structure and function is influenced by histone posttranslational modifications. SET8 (also known as PR-Set7 and SETD8) is a histone methyltransferase that monomethylates histonfe H4-K20. However, a function for SET8 in mammalian cell proliferation has not been determined. We show that sma...

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Detalhes bibliográficos
Main Authors: Jørgensen, Stine, Elvers, Ingegerd, Trelle, Morten Beck, Menzel, Tobias, Eskildsen, Morten, Jensen, Ole Nørregaard, Helleday, Thomas, Helin, Kristian, Sørensen, Claus Storgaard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2373509/
https://ncbi.nlm.nih.gov/pubmed/18166648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706150
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