BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways

We present a novel cell-signaling paradigm in which bone morphogenetic protein 2 (BMP-2) consecutively and interdependently activates the wingless (Wnt)–β-catenin (βC) and Wnt–planar cell polarity (PCP) signaling pathways to facilitate vascular smooth muscle motility while simultaneously suppressing...

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Detalhes bibliográficos
Main Authors: de Jesus Perez, Vinicio A., Ali, Ziad, Alastalo, Tero-Pekka, Ikeno, Fumiaki, Sawada, Hirofumi, Lai, Ying-Ju, Kleisli, Thomas, Spiekerkoetter, Edda, Qu, Xiumei, Rubinos, Laura H., Ashley, Euan, Amieva, Manuel, Dedhar, Shoukat, Rabinovitch, Marlene
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019546/
https://ncbi.nlm.nih.gov/pubmed/21220513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201008060
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