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Angiotensin II Induces afterdepolarizations via reactive oxygen species and calmodulin kinase II signaling

Renin-angiotensin system inhibitors significantly reduce the incidence of arrhythmias. However, the underlying mechanism(s) is not well understood. We aim to test the hypothesis that Ang II induces early afterdepolarizations (EADs) and triggered activities (TAs) via the nicotinamide adenine dinucleo...

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Detalhes bibliográficos
Main Authors: Zhao, Zhenghang, Fefelova, Nadezhda, Shanmugam, Mayilvahanan, Bishara, Peter, Babu, Gopal J., Xie, Lai-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019274/
https://ncbi.nlm.nih.gov/pubmed/21059353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2010.11.001
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