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Suppression of TNF-αand IL-1 Signaling Identifies a Mechanism of Homeostatic Regulation of Macrophages by IL-27
IL-27 is a pleiotropic cytokine with both activating and inhibitory functions on innate and acquired immunity. IL-27 is expressed at sites of inflammation in cytokine-driven autoimmune/inflammatory diseases, such as rheumatoid arthritis, psoriasis, inflammatory bowel disease, and sarcoidosis. Howeve...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019240/ https://ncbi.nlm.nih.gov/pubmed/20971923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001290 |
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