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Suppression of TNF-αand IL-1 Signaling Identifies a Mechanism of Homeostatic Regulation of Macrophages by IL-27

IL-27 is a pleiotropic cytokine with both activating and inhibitory functions on innate and acquired immunity. IL-27 is expressed at sites of inflammation in cytokine-driven autoimmune/inflammatory diseases, such as rheumatoid arthritis, psoriasis, inflammatory bowel disease, and sarcoidosis. Howeve...

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Bibliografski detalji
Glavni autori: Kalliolias, George D., Gordon, Rachael A., Ivashkiv, Lionel B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019240/
https://ncbi.nlm.nih.gov/pubmed/20971923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001290
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