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Top-down morphogenesis of colorectal tumors

One of the fundamental tenets of oncology is that tumors arise from stem cells. In the colon, stem cells are thought to reside at the base of crypts. In the early stages of tumorigenesis, however, dysplastic cells are routinely found at the luminal surface of the crypts whereas the cells at the base...

詳細記述

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書誌詳細
主要な著者: Shih, Ie-Ming, Wang, Tian-Li, Traverso, Giovanni, Romans, Kathy, Hamilton, Stanley R., Ben-Sasson, Shmuel, Kinzler, Kenneth W., Vogelstein, Bert
フォーマット: Artigo
言語:Inglês
出版事項: The National Academy of Sciences 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC30191/
https://ncbi.nlm.nih.gov/pubmed/11226292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051629398
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