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Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations

Many areas of biomedical research depend on the analysis of uncommon variations in individual genes or transcripts. Here we describe a method that can quantify such variation at a scale and ease heretofore unattainable. Each DNA molecule in a collection of such molecules is converted into a single m...

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Detalhes bibliográficos
Main Authors: Dressman, Devin, Yan, Hai, Traverso, Giovanni, Kinzler, Kenneth W., Vogelstein, Bert
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC166396/
https://ncbi.nlm.nih.gov/pubmed/12857956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1133470100
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