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Transforming single DNA molecules into fluorescent magnetic particles for detection and enumeration of genetic variations

Many areas of biomedical research depend on the analysis of uncommon variations in individual genes or transcripts. Here we describe a method that can quantify such variation at a scale and ease heretofore unattainable. Each DNA molecule in a collection of such molecules is converted into a single m...

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Bibliografiset tiedot
Päätekijät: Dressman, Devin, Yan, Hai, Traverso, Giovanni, Kinzler, Kenneth W., Vogelstein, Bert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC166396/
https://ncbi.nlm.nih.gov/pubmed/12857956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1133470100
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