Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity

Glioblastoma (GBM) is the most aggressive primary brain tumor and is resistant to all therapeutic regimens. Relapse occurs regularly and might be caused by a poorly characterized tumor stem cell (TSC) subpopulation escaping therapy. We suggest aldehyde dehydrogenase 1 (ALDH1) as a novel stem cell ma...

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Autori principali: Rasper, Michael, Schäfer, Andrea, Piontek, Guido, Teufel, Julian, Brockhoff, Gero, Ringel, Florian, Heindl, Stefan, Zimmer, Claus, Schlegel, Jürgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
Soggetti:
Basic and Translational Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018920/
https://ncbi.nlm.nih.gov/pubmed/20627895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq070
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