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Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity

Glioblastoma (GBM) is the most aggressive primary brain tumor and is resistant to all therapeutic regimens. Relapse occurs regularly and might be caused by a poorly characterized tumor stem cell (TSC) subpopulation escaping therapy. We suggest aldehyde dehydrogenase 1 (ALDH1) as a novel stem cell ma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rasper, Michael, Schäfer, Andrea, Piontek, Guido, Teufel, Julian, Brockhoff, Gero, Ringel, Florian, Heindl, Stefan, Zimmer, Claus, Schlegel, Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018920/
https://ncbi.nlm.nih.gov/pubmed/20627895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq070
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