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Excursions in polynuclear platinum DNA binding

Polynuclear platinum agents are a structurally unique class of anti-cancer drugs, distinct from the cisplatin family. To describe the chemistry and biology of this class, it was necessary to challenge the accepted paradigms for the structure–activity relationships; design new chemotypes and delineat...

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Détails bibliographiques
Auteurs principaux: Mangrum, John B., Farrell, Nicholas P.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018806/
https://ncbi.nlm.nih.gov/pubmed/20694266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc01254h
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