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Nuclear FoxO1 inflames insulin resistance
FoxO1 regulates the transcription of genes involved in diabetes, cancer and ageing. In this issue of The EMBO Journal, Olefsky and colleagues report that FoxO1 also causes inflammation by regulating the pro-inflammatory Tlr4 signalling pathway in macrophages. Insulin-mediated activation of Akt inact...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3018800/ https://ncbi.nlm.nih.gov/pubmed/21157481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.305 |
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