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Role of the forkhead protein FoxO1 in β cell compensation to insulin resistance
Diabetes is associated with defective β cell function and altered β cell mass. The mechanisms regulating β cell mass and its adaptation to insulin resistance are unknown. It is unclear whether compensatory β cell hyperplasia is achieved via proliferation of existing β cells or neogenesis from progen...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370178/ https://ncbi.nlm.nih.gov/pubmed/16485043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24967 |
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