Role of the forkhead protein FoxO1 in β cell compensation to insulin resistance

Diabetes is associated with defective β cell function and altered β cell mass. The mechanisms regulating β cell mass and its adaptation to insulin resistance are unknown. It is unclear whether compensatory β cell hyperplasia is achieved via proliferation of existing β cells or neogenesis from progen...

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Main Authors: Okamoto, Haruka, Hribal, Marta Letizia, Lin, Hua V., Bennett, William R., Ward, Andrew, Accili, Domenico
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2006
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370178/
https://ncbi.nlm.nih.gov/pubmed/16485043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24967
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