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USP7 Attenuates Hepatic Gluconeogenesis Through Modulation of FoxO1 Gene Promoter Occupancy

Hepatic forkhead protein FoxO1 is a key component of systemic glucose homeostasis via its ability to regulate the transcription of rate-limiting enzymes in gluconeogenesis. Important in the regulation of FoxO1 transcriptional activity are the modifying/demodifying enzymes that lead to posttranslatio...

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Hlavní autoři: Hall, Jessica A., Tabata, Mitsuhisa, Rodgers, Joseph T., Puigserver, Pere
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4042075/
https://ncbi.nlm.nih.gov/pubmed/24694308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1420
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