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Genome-wide analysis of FoxO1 binding in hepatic chromatin: Potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis

The forkhead transcription factor FoxO1 is a critical regulator of hepatic glucose and lipid metabolism, and dysregulation of FoxO1 function has been implicated in diabetes and insulin resistance. We globally identified FoxO1 occupancy in mouse hepatic chromatin on a genome-wide level by chromatin i...

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Detalhes bibliográficos
Main Authors: Shin, Dong-Ju, Joshi, Pujan, Hong, Seung-Hyun, Mosure, Kathleen, Shin, Dong-Guk, Osborne, Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3526316/
https://ncbi.nlm.nih.gov/pubmed/23066095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks932
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