Genetic disruption of PPARδ decreases the tumorigenicity of human colon cancer cells

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that have been implicated in a variety of biologic processes. The PPARδ isotype was recently proposed as a downstream target of the adenomatous polyposis coli (APC)/β-catenin pathway in colorectal carcinogenesis. To ev...

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Bibliographic Details
Main Authors: Park, Ben Ho, Vogelstein, Bert, Kinzler, Kenneth W.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC30184/
https://ncbi.nlm.nih.gov/pubmed/11226285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051630998
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