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DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis
In the autoimmune syndrome rheumatoid arthritis (RA), T cells and T-cell precursors have age-inappropriate shortening of telomeres and accumulate deoxyribonucleic acid (DNA) double strand breaks. Whether damaged DNA elicits DNA repair activity and how this affects T-cell function and survival is unk...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
WILEY-VCH Verlag
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017722/ https://ncbi.nlm.nih.gov/pubmed/20878914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201000096 |
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