Foxp3 regulates megakaryopoiesis and platelet function

Platelets are crucial for hemostasis and are vital regulators of inflammation. Foxp3 is a key transcription factor for T regulatory cell development. Humans with IPEX (immune dysregulation, polyendocrinopathy, enteropathy, x-linked) and the scurfy (Foxp3(sf)) mouse have mutations in the Foxp3 gene t...

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Detalhes bibliográficos
Main Authors: Bernard, Jamie J., Seweryniak, Kathryn E., Koniski, Anne D., Spinelli, Sherry L., Blumberg, Neil, Francis, Charles W., Taubman, Mark B., Palis, James, Phipps, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017715/
https://ncbi.nlm.nih.gov/pubmed/19661482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.193805
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