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The Feverfew plant-derived compound, parthenolide enhances platelet production and attenuates platelet activation through NF-κB inhibition

INTRODUCTION: Few treatments are available that can safely and effectively stimulate new platelet production for thrombocytopenic patients. Additionally, recipients of transfused platelets may experience an inflammatory response due to stored platelets becoming unnecessarily activated, thus creating...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sahler, Julie, Bernard, Jamie J., Spinelli, Sherry L., Blumberg, Neil, Phipps, Richard P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081947/
https://ncbi.nlm.nih.gov/pubmed/21272923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2010.12.013
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