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NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets
The primary toll-like receptor (TLR)-mediated immune cell response pathway common for all TLRs is MyD88-dependent activation of NF-κB, a seminal transcription factor for many chemokines and cytokines. Remarkably, anucleate platelets express the NF-κB machinery, whose role in platelets remains poorly...
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| Gepubliceerd in: | Front Immunol |
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| Hoofdauteurs: | , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Frontiers Media S.A.
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5292648/ https://ncbi.nlm.nih.gov/pubmed/28220122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00085 |
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