LPS stimulation of purified human platelets is partly dependent on plasma soluble CD14 to secrete their main secreted product, soluble-CD40-Ligand

BACKGROUND: Platelets are instrumental to primary haemostasis; in addition, as they are central to endothelium vascular repair, they play a role in physiological inflammation. Platelets have also been demonstrated to be key players in innate immunity and inflammation, expressing Toll-like receptors...

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Publicat a:BMC Immunol
Autors principals: Damien, Pauline, Cognasse, Fabrice, Eyraud, Marie-Ange, Arthaud, Charles-Antoine, Pozzetto, Bruno, Garraud, Olivier, Hamzeh-Cognasse, Hind
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4322959/
https://ncbi.nlm.nih.gov/pubmed/25636826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-015-0067-2
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