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Identification of two subpopulations of purified human blood B cells, CD27(−) CD23(+) and CD27(high) CD80(+), that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6

B-cell expression of certain Toll-like receptors (TLRs) is important in linking innate and adaptive immune responses in normal and pathological conditions. The expression of TLR9 plays a role in the recognition of conserved pathogen motifs in a manner that is dependent on B-cell localization, deduce...

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Detalhes bibliográficos
Main Authors: Cognasse, Fabrice, Hamzeh-Cognasse, Hind, Lafarge, Sandrine, Chavarin, Patricia, Pozzetto, Bruno, Richard, Yolande, Garraud, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669146/
https://ncbi.nlm.nih.gov/pubmed/18445007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02844.x
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