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Identification of two subpopulations of purified human blood B cells, CD27(−) CD23(+) and CD27(high) CD80(+), that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6
B-cell expression of certain Toll-like receptors (TLRs) is important in linking innate and adaptive immune responses in normal and pathological conditions. The expression of TLR9 plays a role in the recognition of conserved pathogen motifs in a manner that is dependent on B-cell localization, deduce...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669146/ https://ncbi.nlm.nih.gov/pubmed/18445007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02844.x |
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