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The platelet as an immune cell--CD40 ligand and transfusion immunomodulation

The discovery that platelets possess cell membrane, cytoplasmic and secreted forms of the co-stimulatory molecule CD40 ligand (CD40L, also known as CD154) has led to a revolution in the view of this anucleate, differentiated cell fragment, previously thought only to be involved in blood clotting (he...

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Bibliographic Details
Main Authors: Blumberg, Neil, Spinelli, Sherry L., Francis, Charles W., Taubman, Mark B., Phipps, Richard P.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891252/
https://ncbi.nlm.nih.gov/pubmed/19184537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12026-009-8106-9
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