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Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase
To prevent potential errors in protein synthesis, some aminoacyl-transfer RNA (tRNA) synthetases have evolved editing mechanisms to hydrolyze misactivated amino acids (pre-transfer editing) or misacylated tRNAs (post-transfer editing). Class Ia leucyl-tRNA synthetase (LeuRS) may misactivate various...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017609/ https://ncbi.nlm.nih.gov/pubmed/20805241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq763 |
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