Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase

To prevent potential errors in protein synthesis, some aminoacyl-transfer RNA (tRNA) synthetases have evolved editing mechanisms to hydrolyze misactivated amino acids (pre-transfer editing) or misacylated tRNAs (post-transfer editing). Class Ia leucyl-tRNA synthetase (LeuRS) may misactivate various...

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Hlavní autoři: Chen, Xin, Ma, Jing-Jing, Tan, Min, Yao, Peng, Hu, Qing-Hua, Eriani, Gilbert, Wang, En-Duo
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Nucleic Acid Enzymes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017609/
https://ncbi.nlm.nih.gov/pubmed/20805241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq763
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