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Modulation of Aminoacylation and Editing Properties of Leucyl-tRNA Synthetase by a Conserved Structural Module

A conserved structural module following the KMSKS catalytic loop exhibits α-α-β-α topology in class Ia and Ib aminoacyl-tRNA synthetases. However, the function of this domain has received little attention. Here, we describe the effect this module has on the aminoacylation and editing capacities of l...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yan, Wei, Ye, Qing, Tan, Min, Chen, Xi, Eriani, Gilbert, Wang, En-Duo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424357/
https://ncbi.nlm.nih.gov/pubmed/25817995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.639492
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