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Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain
The editing function of aminoacyl-tRNA synthetases (aaRSs) is indispensible for formation of the correct aminoacyl-tRNAs. Editing deficiency may lead to growth inhibition and the pathogenesis of various diseases. Herein, we confirmed that norvaline (Nva) but not isoleucine or valine is the major thr...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499588/ https://ncbi.nlm.nih.gov/pubmed/28575390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx487 |
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