Effects of methimazole on the elimination of irinotecan

PURPOSE: To study the possible pharmacokinetic and pharmacodynamic interactions between irinotecan and methimazole. METHODS: A patient treated for colorectal cancer with single agent irinotecan received methimazole co-medication for Graves’ disease. Irinotecan pharmacokinetics and side effects were...

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Main Authors: van der Bol, Jessica M., Visser, Theo J., Loos, Walter J., de Jong, Floris A., Wiemer, Erik A. C., van Aken, Maarten O., Planting, Andre S., Schellens, Jan H., Verweij, Jaap, Mathijssen, Ron H. J.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2010
主題:
Short Communication
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016232/
https://ncbi.nlm.nih.gov/pubmed/20680278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1414-x
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