Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study

PURPOSE: Response to anticancer therapy is believed to be directly related to the concentration of the anticancer drug in the tumor itself. Assessment of intra-tumor drug pharmacokinetics can be helpful to gain more insight into mechanisms involved in the (in)sensitivity of tumors to anticancer ther...

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Main Authors: Konings, Inge R. H. M., Sleijfer, Stefan, Mathijssen, Ron H. J., de Bruijn, Peter, Ghobadi Moghaddam-Helmantel, Inge M., van Dam, Linda M., Wiemer, Erik A. C., Verweij, Jaap, Loos, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082021/
https://ncbi.nlm.nih.gov/pubmed/20652702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1400-3
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