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Effects of methimazole on the elimination of irinotecan

PURPOSE: To study the possible pharmacokinetic and pharmacodynamic interactions between irinotecan and methimazole. METHODS: A patient treated for colorectal cancer with single agent irinotecan received methimazole co-medication for Graves’ disease. Irinotecan pharmacokinetics and side effects were...

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Detalhes bibliográficos
Main Authors: van der Bol, Jessica M., Visser, Theo J., Loos, Walter J., de Jong, Floris A., Wiemer, Erik A. C., van Aken, Maarten O., Planting, Andre S., Schellens, Jan H., Verweij, Jaap, Mathijssen, Ron H. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016232/
https://ncbi.nlm.nih.gov/pubmed/20680278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1414-x
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