Effects of Mannose-Binding Lectin Polymorphisms on Irinotecan-Induced Febrile Neutropenia

OBJECTIVE. Mannose-binding lectin (MBL) is important in the innate immune response. MBL2 gene polymorphisms affect MBL expression, and genotypes yielding low MBL levels have been associated with an elevated risk for infections in hematological cancer patients undergoing chemotherapy. However, these...

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Detalhes bibliográficos
Main Authors: van der Bol, Jessica M., de Jong, Floris A., van Schaik, Ron H., Sparreboom, Alex, van Fessem, Marianne A., van de Geijn, Fleur E., van Daele, Paul L., Verweij, Jaap, Sleijfer, Stefan, Mathijssen, Ron H.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2010
Assuntos:
Clinical Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3227891/
https://ncbi.nlm.nih.gov/pubmed/20930093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2010-0033
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