Properties of the nucleic-acid bases in free and Watson-Crick hydrogen-bonded states: computational insights into the sequence-dependent features of double-helical DNA

The nucleic-acid bases carry structural and energetic signatures that contribute to the unique features of genetic sequences. Here, we review the connection between the chemical structure of the constituent nucleotides and the polymeric properties of DNA. The sequence-dependent accumulation of charg...

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Detalhes bibliográficos
Main Authors: Srinivasan, A. R., Sauers, Ronald R., Fenley, Marcia O., Boschitsch, Alexander H., Matsumoto, Atsushi, Colasanti, Andrew V., Olson, Wilma K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2009
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016052/
https://ncbi.nlm.nih.gov/pubmed/21218180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-008-0003-2
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