Trypanosoma cruzi infection induces a massive extrafollicular and follicular splenic B-cell response which is a high source of non-parasite-specific antibodies

Acute infection with Trypanosoma cruzi, the aetiological agent of Chagas’ disease, results in parasitaemia and polyclonal lymphocyte activation. It has been reported that polyclonal B-cell activation is associated with hypergammaglobulinaemia and delayed parasite-specific antibody response. In the p...

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Bibliografiske detaljer
Main Authors: Bermejo, Daniela A, Amezcua Vesely, María C, Khan, Mahmood, Acosta Rodríguez, Eva V, Montes, Carolina L, Merino, Maria C, Toellner, Kai Michael, Mohr, Elodie, Taylor, Dale, Cunningham, Adam F, Gruppi, Adriana
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2011
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015082/
https://ncbi.nlm.nih.gov/pubmed/20875075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03347.x
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