IL-17RA Signaling Reduces Inflammation and Mortality during Trypanosoma cruzi Infection by Recruiting Suppressive IL-10-Producing Neutrophils

Members of the IL-17 cytokine family play an important role in protection against pathogens through the induction of different effector mechanisms. We determined that IL-17A, IL-17E and IL-17F are produced during the acute phase of T. cruzi infection. Using IL-17RA knockout (KO) mice, we demonstrate...

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Main Authors: Tosello Boari, Jimena, Amezcua Vesely, María Carolina, Bermejo, Daniela Andrea, Ramello, Maria Cecilia, Montes, Carolina Lucía, Cejas, Hugo, Gruppi, Adriana, Acosta Rodríguez, Eva Virginia
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3343119/
https://ncbi.nlm.nih.gov/pubmed/22577359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002658
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