BAFF Mediates Splenic B Cell Response and Antibody Production in Experimental Chagas Disease

BACKGROUND: B cells and antibodies are involved not only in controlling the spread of blood circulating Trypanosoma cruzi, but also in the autoreactive manifestations observed in Chagas disease. Acute infection results in polyclonal B cell activation associated with hypergammaglobulinemia, delayed s...

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Hauptverfasser: Bermejo, Daniela A., Amezcua-Vesely, María C., Montes, Carolina L., Merino, María C., Gehrau, Ricardo C., Cejas, Hugo, Acosta-Rodríguez, Eva V., Gruppi, Adriana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864296/
https://ncbi.nlm.nih.gov/pubmed/20454564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000679
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