Trypanosoma cruzi infection induces a massive extrafollicular and follicular splenic B-cell response which is a high source of non-parasite-specific antibodies

Acute infection with Trypanosoma cruzi, the aetiological agent of Chagas’ disease, results in parasitaemia and polyclonal lymphocyte activation. It has been reported that polyclonal B-cell activation is associated with hypergammaglobulinaemia and delayed parasite-specific antibody response. In the p...

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Main Authors: Bermejo, Daniela A, Amezcua Vesely, María C, Khan, Mahmood, Acosta Rodríguez, Eva V, Montes, Carolina L, Merino, Maria C, Toellner, Kai Michael, Mohr, Elodie, Taylor, Dale, Cunningham, Adam F, Gruppi, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3015082/
https://ncbi.nlm.nih.gov/pubmed/20875075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03347.x
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